Endocrine Abstracts

Pancreatic neuroendocrine tumors constitute a disease with steadily increasing prevalence worldwide in part owing to the increased detection of early stage disease. Here we present the case of a 49 year old male patient, who was admitted with clinical, laboratory and CT features of acute pancreatitis. A clear cause for the pancreatitis could not be detected. Excessive alcohol intake was reliably denied, and the patient did not take any drugs. Gallbladder and bile ducts were in...

Fluid and electrolyte disturbances are a challenging problem of inpatients, especially in those subpopulations, in whom the electrolyte imbalance is involved in the pathogenesis of the primary disease. Here we present the case of a 58 year old woman, with ongoing alcohol abuse on a daily basis, who was admitted with progressive fatigue and dysphagia. At the admission BMI was 17.8 kg/m2, and the patient presented deficiency of vitamins A, B, and D. The diagnostic pro...

Background and aims: Non alcoholic fatty liver disease (NAFLD) is highly associated with other components of the metabolic syndrome, in particular obesity and diabetes. However, systematic network medicine approach of the complex phenotypic dependencies and comorbidities has yet to be performed. Our aim now is to identify novel drug targets for NAFLD treatment by a systematic in silico network analysis.Methods: We constructed an interaction network of cu...